#27: She Directs Big Starring Tom Hanks in 1988
In 1988, she directs the fantasy comedy Big, starring Tom Hanks as a boy who suddenly wakes up in an adult body. The film becomes a massive commercial success and quickly stands out as one of the most popular movies of the year.

Big earns more than $100 million at the U.S. box office, making her the first woman to direct a film reaching that milestone. The success dramatically raises her profile in Hollywood and establishes her as a major studio director.
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